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The safety and efficacy of Onivyde (irinotecan liposome ... | 合法藥品大搜索

The safety and efficacy of Onivyde (irinotecan liposome ...

由FCPasseroJr著作·2016·被引用61次—Introduction:Patientswithadvancedandmetastaticpancreaticcancerrefractorytogemcitabinebasedtherapyhaveadismalprognosisandlimitedtherapeutic ...

 The safety and efficacy of Onivyde (irinotecan liposome ...

Introduction: Patients with advanced and metastatic pancreatic cancer refractory to gemcitabine based therapy have a dismal prognosis and limited therapeutic options. Recently, the FDA approved nanoliposomal irinotecan combined with fluorouracil/folinic acid for such patients based upon results of the NAPOLI-1 study which showed this regimen compared to fluorouracil/folinic acid significantly prolonged progression free survival (3.1 vs. 1.5 months) and overall survival (6.2 vs. 4.1 months).

Areas covered: The pharmacokinetic and pharmacogenetic characteristics of this novel formulation of irinotecan, its safety profile, and use in a clinical context for patients with pancreatic cancer are reviewed. Expert commentary: Nanoliposomal irinotecan, in combination with 5-FU/folinic acid, represents an important step forward in improving second line treatment options in patients with progression of metastat...

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Onivyde (irinotecan liposome injection) for the Treatment of ... | 合法藥品大搜索
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Metastatic Pancreatic Cancer Treatment Option | 合法藥品大搜索
ONIVYDE (irinotecan liposome injection) is proven to help people with metastatic pancreatic cancer, who previously received gemcitabine chemotherapy, live ... Read More
Liposomal Irinotecan | 合法藥品大搜索
由 JE Frampton 著作 · 2020 · 被引用 4 次 — Key words were liposomal irinotecan, Onivyde, pancreatic cancer. Records were limited to those in ... Read More
FDA grants fast track designation to Onivyde for advanced ... | 合法藥品大搜索
2020年6月17日 — “Since the initial approval of Onivyde in metastatic pancreatic cancer, we have continued to dedicate our research efforts to better understand ... Read More
Pancreatic Cancer Study Program – National Institute of ... | 合法藥品大搜索
ONIVYDETM. One of the most exciting achievement of NICR in the past years is the success of a global, randomized phase III NAPOLI- ... Read More
NAPOLI | 合法藥品大搜索
由 A Wang-Gillam 著作 · 2019 · 被引用 65 次 — Longer overall survival in metastatic pancreatic cancer post–first line ... Liposomal irinotecan (nal-IRI; Onivyde®; Ipsen Biopharmaceuticals, Inc. Read More
Onivyde (Irinotecan Liposome Injection) a New Treatment ... | 合法藥品大搜索
由 LA Raedler 著作 · 被引用 1 次 — The FDA approval of irinotecan liposome injection has added a new treatment option for patients with pancreatic cancer. The drug is only approved for use in ... Read More
Ipsen receives FDA Fast Track designation for liposomal ... | 合法藥品大搜索
2020年6月17日 — “Since the initial approval of ONIVYDE® in metastatic pancreatic cancer, we have continued to dedicate our research efforts to better ... Read More
The safety and efficacy of Onivyde (irinotecan liposome ... | 合法藥品大搜索
由 FC Passero Jr 著作 · 2016 · 被引用 61 次 — Introduction: Patients with advanced and metastatic pancreatic cancer refractory to gemcitabine based therapy have a dismal prognosis and limited therapeutic ... Read More
Liposomal Irinotecan Regimen Pushes Toward Frontline ... | 合法藥品大搜索
2020年8月18日 — ... the NAPOLI-1 and NAPOLI-3 trials in metastatic pancreatic cancer, ... In October 2015, the FDA approved liposomal irinotecan (Onivyde) in ... Read More
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