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Proteoglycan | 合法藥品大搜索

Proteoglycan

Function[edit].Proteoglycansareamajorcomponentoftheanimalextracellularmatrix,the"filler"substanceexistingbetweencellsinanorganism.Heretheyform ...

 Proteoglycan

Class of compounds

Proteoglycans are proteins[1] that are heavily glycosylated. The basic proteoglycan unit consists of a "core protein" with one or more covalently attached glycosaminoglycan (GAG) chain(s).[2] The point of attachment is a serine (Ser) residue to which the glycosaminoglycan is joined through a tetrasaccharide bridge (e.g. chondroitin sulfate-GlcA-Gal-Gal-Xyl-PROTEIN). The Ser residue is generally in the sequence -Ser-Gly-X-Gly- (where X can be any amino acid residue but proline), although not every protein with this sequence has an attached glycosaminoglycan. The chains are long, linear carbohydrate polymers that are negatively charged under physiological conditions due to the occurrence of sulfate and uronic acid groups. Proteoglycans occur in connective tissue.

Proteoglycans are cate...

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蛋白聚糖 | 合法藥品大搜索
蛋白聚糖（英語：proteoglycan）是被大量糖基化了的糖蛋白。基本的蛋白聚糖單位由一個「核心蛋白質」與一個或多個共價結合著的糖胺聚糖鏈所組成。附著點是 ... Read More
Proteoglycan | 合法藥品大搜索
Function[edit]. Proteoglycans are a major component of the animal extracellular matrix, the "filler" substance existing between cells in an organism. Here they form ... Read More
Proteoglycans | 合法藥品大搜索
Proteoglycans (PGs) are a widely diverse family of macromolecules copiously found on cell membranes and in the (ECM) of many tissues throughout the ... Read More
Proteoglycan | 合法藥品大搜索
Proteoglycans. A proteoglycan consists of a core protein having a variable number of GAG side chains [21] (Table 14.1) ... Read More
An Introduction to Proteoglycans and Their Localization | 合法藥品大搜索
由 JR Couchman 著作 · 2012 · 被引用 151 次 — By definition, proteoglycans consist of a core protein to which one or more glycosaminoglycan chains are covalently attached. Glycosaminoglycans (GAGs) ... Read More
Proteoglycans and Glycosaminoglycans | 合法藥品大搜索
由 A Varki 著作 · 1999 · 被引用 16 次 — Proteoglycans consist of a core protein and one or more covalently attached GAG chains (Figure 11.2). GAGs are linear polysaccharides, whose building blocks ( ... Read More
Function of proteoglycans in the extracellular matrix | 合法藥品大搜索
由 M Yanagishita 著作 · 1993 · 被引用 346 次 — Proteoglycans are glycosylated proteins which have covalently attached highly anionic glycosaminoglycans. Many forms of proteoglycans are present in virtually ... Read More
Structure and Function of Proteoglycans | 合法藥品大搜索
2019年7月9日 — Proteoglycans are ubiquitous molecules that function as critical components of the extracellular matrix. These proteins are composed of ... Read More
Proteoglycans | 合法藥品大搜索
Proteoglycans. Proteoglycans (mucoproteins) are formed of glycosaminoglycans (GAGs) covalently attached to the core proteins. They are found in all ... Read More
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