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Anesthesia of surgery was a great contribution to medical development. Surgeon can make superior medical treatment for patient during operation by anesthesia; the patients have no sense of pain at all in the general anaesthesia. Utilizing the characteristics of the medicine anesthetist could emphasize the three momentous conditions while anaesthetizing such as unconsciousness, analgesia and muscle relaxation. For this reason the dose of drug needs to be up to right amount of surgery, and we define that complete anesthesia. Evaluation for the depth of anesthesia is dependent on patient’s physiological signal and the sophisticated anesthetist’s experience to offer proper medicine that make patients have the best and safest anesthesia process. According to previously studies, heart rate variability (HRV) is a promising physiological signal for assessing autonomous nervous system act...