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由黃俊瑋著作·2014—抗生素的發展在近年來日漸趨緩，短期內能上市的新抗生素寥寥無幾；然而細菌的抗藥性卻逐年攀升使得臨床醫師在治療多重抗藥性(multi-drug)細菌感染時能夠 ...

According to medical evolution, different antibiotics have been discovered and are used to treat serious infections. However, antibiotic resistant strains are increasingly prevalent and become a global health problem. Due to development of new antibiotic can take years and millions of dollars, the rational use of old antibiotics, like polymyxins, fusidic acid and fosfomycin may be a short-term solution. Fosfomycin has been used successfullyfor the treatment of urinary tract infections for a long time; fosfomycin could be a suitable candidate for the treatment of multidrug-resistant pathogens or extended-spectrumβ-lactamases Enterobacteriaceae. In order to evaluate the efficacy of fosfomycin against extended-spectrumβ-lactamases Enterobacteriaceae in southern Taiwan,this study collected different specimens from human and livestock.The susceptible rates of fosfomycin were 94% (115/123), and 77% (17/22)for ESBL-producin...