Indocin (indomethacin) Injection for Many Types of Arthritis ... | 合法藥品大搜索

2021年4月16日—Indocin(indomethacin)forinjectionisusedtotreatosteoarthritis,rheumatoidarthritis,goutyarthritisorankylosingspondylitis.Learnsideeffects ...

In a double-blind, placebo-controlled trial of 405 premature infants weighing less than or equal to 1750 g with evidence of large ductal shunting, in those neonates treated with indomethacin (n=206), there was a statistically significantly greater incidence of bleeding problems, including gross or microscopic bleeding into the gastrointestinal tract[1], oozing from the skin after needle stick, pulmonary hemorrhage[2], and disseminated intravascular coagulopathy. There was no statistically significant difference between treatment groups with reference to intracranial hemorrhage.

The neonates treated with indomethacin for injection also had a significantly higher incidence of transient oliguria[3] and elevations of serum creatinine (greater than or equal to 1.8 mg/dL) than did the neonates treated with placebo.

The incidences of retrolental fibroplasia (grades III and IV) and pneumothorax in neonates treat...