Rifinah 150mg100mg Tablets | 合法藥品大搜索

Thisinformationisintendedforusebyhealthprofessionals·Rifinah150/100mgTablets·Activesubstances(pertablet):·Coatedtablet·4.1Therapeuticindications.

Interference with laboratory and diagnostic tests

Therapeutic levels of rifampicin have been shown to inhibit standard microbiological assays for serum folate and Vitamin B12. Thus, alternative assay methods should be considered. Transient elevation of BSP and serum bilirubin has been reported. Rifampicin may impair biliary excretion of contrast media used for visualization of the gallbladder, due to competition for biliary excretion. Therefore, these tests should be performed before the morning dose of rifampicin.

Interactions with Other Medicinal Products

When Rifinah is given concomitantly with the combination saquinavir/ritonavir, the potential for hepatotoxicity is increased. Therefore, concomitant use of Rifinah with saquinavir/ritonavir is contraindicated (see section 4.3).

Cytochrome P-450 enzyme interaction

Rifampicin is known to induce, and i...