Alteplase | 合法藥品大搜索

Alteplase(t-PA)isathrombolyticmedication,usedtotreatacuteischemicstroke,acuteST-elevationmyocardialinfarctionpulmonaryembolismassociatedwith ...

Alteplase (t-PA) is a thrombolytic medication, used to treat acute ischemic stroke, acute ST-elevation myocardial infarction (a type of heart attack), pulmonary embolism associated with low blood pressure, and blocked central venous catheter.[5] It is given by injection into a vein or artery.[5] Alteplase is the same as the normal human plasminogen activator produced in vascular endothelial cells[6] and is synthesized via recombinant DNA technology in Chinese hamster ovary cells (CHO). Alteplase causes the breakdown of a clot by inducing fibrinolysis.[7]

Alteplase is mainly used to treat acute ischemic stroke, acute myocardial infarction, acute massive pulmonary embolism, and blocked catheters.[5][1][2] Similar to other thrombolytic drugs, alteplase is used to dissolve clots to restore tissue perfusion, but this can vary depending on the pathology.[8][9][10] ...