Invasive Haemophilus Influenzae Type b (Hib) | 合法藥品大搜索

In2005,theself-payfive-in-oneplushepatitisBvaccinewasintroduced,thebirthcohortvaccinationratewasmorethan50%andincreasedyearbyyearsince ...

Background

Haemophilus influenzae is a gram-negative coccobacillus. It can be divided into encapsulated and non-encapsulated. Non-encapsulated organism is unable to subtype and encapsulated strains can be divided into six serologic types, a-f, of which b type is the most common cause of severe infant disease.

Hib is a serious infectious disease, mainly occurs in children aged less than 5 years. It causes invasive disease such as meningitis, bacteremia, pneumonia, cellulitis, bacterial arthritis, osteomyelitis, and epiglottis, etc. The incidence is considerably different in different regions. The most common presentation of invasive Hib disease is meningitis, which accounted for 50%-65%. The mortality rate is about 2% to 5%. About 15-30% survivors will develop sequelae such as hydrocephalus, encephalitis, ataxia, hearing damage, mental retardation and paralysis. It not only causes severely impact on personal health, but also increases the ...