VENCLEXTA® (venetoclax tablets) | 合法藥品大搜索

DiscoverVENCLEXTA®(venetoclaxtablets):Anoraltherapytohelpyoufightcertainbloodcancers.SeefullPrescribingandSafetyinformation.

Important Safety Information What is the most important information I should know about VENCLEXTA?

VENCLEXTA can cause serious side effects, including:

Tumor lysis syndrome (TLS). TLS is caused by the fast breakdown of cancer cells. TLS can cause kidney failure, the need for dialysis treatment, and may lead to death. Your healthcare provider will do tests to check your risk of getting TLS before you start taking VENCLEXTA. You will receive other medicines before starting and during treatment with VENCLEXTA to help reduce your risk of TLS. You may also need to receive intravenous (IV) fluids into your vein. Your healthcare provider will do blood tests to check for TLS when you first start treatment and during treatment with VENCLEXTA. It is important to keep your appointments for blood tests. Tell your healthcare provider right away if you have any symptoms of TLS during treatment wit...

Azacitidine and Venetoclax in Previously Untreated Acute ... | 合法藥品大搜索

由 CD DiNardo 著作 · 2020 · 被引用 249 次 — Abstract Background Older patients with acute myeloid leukemia (AML) have a dismal prognosis, even after treatment with a hypomethylating ... Read More

VENCLEXTA® (venetoclax tablets) for Acute Myeloid ... | 合法藥品大搜索

AML LIVE LONGER. In a clinical study of 431 adults with newly diagnosed acute myeloid leukemia (AML), 286 patients received VENCLEXTA + azacitidine ... Read More

VENCLEXTA® (venetoclax tablets) | 合法藥品大搜索

Discover VENCLEXTA® (venetoclax tablets): An oral therapy to help you fight certain blood cancers. See full Prescribing and Safety information. Read More

FDA grants regular approval to venetoclax in combination for ... | 合法藥品大搜索

2020年10月16日 — FDA grants regular approval to venetoclax in combination for untreated acute myeloid leukemia ... Venetoclax was initially granted accelerated ... Read More

Venetoclax for AML | 合法藥品大搜索

由 DA Pollyea 著作 · 2019 · 被引用 48 次 — The first clinical trial of venetoclax in patients with AML was a phase 2 single-agent study in predominately relapsed and refractory patients. This ... Read More

Venetoclax | 合法藥品大搜索

由 B Samra 著作 · 2020 · 被引用 2 次 — Venetoclax is an oral BH3 mimetic highly selective for BCL-2 without targeting BCL-XL, with dramatic activity in CLL, notably independent of TP53 ... Read More

VENCLEXTA® (venetoclax) Receives FDA Full Approval for ... | 合法藥品大搜索

2020年10月16日 — VENCLEXTA® (venetoclax) Receives FDA Full Approval for Acute Myeloid Leukemia (AML) · to treat adults with chronic lymphocytic leukemia ( ... Read More

Venetoclax | 合法藥品大搜索

由 B Samra 著作 · 2020 · 被引用 2 次 — Anti-apoptotic proteins include BCL-2, MCL-1, BCL-XL, BCL-W and BFL-1. In AML, BCL-2 is upregulated. Venetoclax ... Read More

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