Tenoxicam及Piroxicam治療退化性關節炎的比較性評估 | 合法藥品大搜索

兩組中各有一名病人發生腸胃副作用，Piroxicam組中有一例發生皮膚疹及臉部血管性水腫而停藥。並沒有發生系統性不良反應者，實驗室檢查數據在治療前後亦無 ...

In this open randomized comparative study, thirty-nine patients suffering from osteoarthritis were treated for four weeks with tenoxicam (TLC) 20 mg once daily (20 cases) or a comparative drug piroxicam (PRC) 10 mg twice daily (19 cases). Significant improvement was noted in both groups in terms of decreased joint pain at rest and pain on motion subjectively as well as objectively in terms of decreased joint tenderness and mobility limitation. The global assessment, poor or fair in all patients before treatment, turned out to be good or very good at the end of the study in 60% patients of the TLC group and 53% patients of the PRC group, respectively. One patient in each group developed gastrointestinal upset. One patient in the PRC group developed face angioedema and skin rash which l...