Parsabiv (etelcalcetide) dosing | 合法藥品大搜索

Medscape-SecondaryhyperparathyroidismdosingforParsabiv(etelcalcetide),frequency-basedadverseeffects,comprehensiveinteractions,contraindications​ ...

Hypersensitivity to etelcalcetide or any of its excipients

Cases of hypotension, congestive heart failure, and decreased myocardial performance reported in clinical trials; reductions in corrected serum calcium may be associated with congestive heart failure, however, a causal relationship could not be completely excluded closely monitor for worsening signs and symptoms of heart failure

Adynamic bone may develop if PTH levels are chronically suppressed; if PTH levels decrease below the recommended target range, the dose of vitamin D sterols and/or etelcalcetide should be reduced or discontinued; after discontinuation, resume therapy at a lower dose to maintain PTH levels in the target range

Rare reports of upper GI bleeding occurred during clinical trials; the exact cause of the GI bleeds were unknown and there were too few cases t...