Von Willebrand factor | 合法藥品大搜索

vonWillebrandfactor(VWF)isabloodglycoproteininvolvedinhemostasis.Itisdeficientand/ordefectiveinvonWillebranddiseaseandisinvolvedinmany ...

Mammalian protein involved in blood clotting

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Von Willebrand factor (VWF) (German: [fɔn ˈvɪləbʁant]) is a blood glycoprotein that promotes hemostasis, specifically, platelet adhesion. It is deficient and/or defective in von Willebrand disease and is involved in many other diseases, including thrombotic thrombocytopenic purpura, Heydes syndrome, and possibly hemolytic–uremic syndrome.[5] Increased plasma levels in many cardiovascular, neoplastic, metabolic (e.g. diabetes), and connective tissue diseases are presumed to arise from adverse changes to the endothelium, and may predict an increa...