Chemokine Receptor CCR5 Antagonist Maraviroc | 合法藥品大搜索

Maraviroc is an entry inhibitor. Specifically, maraviroc is a negative allosteric modulator of the CCR5 receptor, which is found on the surface of certain human cells. Read More

7.1Pharmacology ... Maraviroc is a chemokine receptor antagonist drug developed by the drug company Pfizer that is designed to act against HIV by interfering with ... Read More

What is maraviroc? ... Maraviroc is a prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of HIV infection in adults and ... Read More

Mechanism of Action. Maraviroc selectively binds to the human chemokine receptor CCR5, which is present on the cell membrane. This binding prevents the​ ... Read More

Maraviroc (brand-named Selzentry, or Celsentri outside the U.S.) is a chemokine receptor antagonist drug developed by the drug company Pfizer that is ... Read More

Maraviroc binds to the active site pocket of chemokine receptor CCR5 making the receptor inactive. Maraviroc is a CCR5 chemokine receptor antagonist, and ... Read More

由 SM Woollard 著作 · 2015 · 被引用 141 次 — CCR5 antagonists bind to CCR5 to prevent viral entry. Maraviroc (MVC) is the only CCR5 antagonist currently approved by the United States ... Read More

由 GG Xu 著作 · 2014 · 被引用 30 次 — Maraviroc is a highly potential microbicide candidate in clinical development. Veazey et al firstly tested the ability of Maraviroc as a vaginal microbicide to prevent ... Read More

Maraviroc belongs to a class of drugs known as entry inhibitors. It works by blocking the HIV virus from infecting healthy immune cells (T-cells).Maraviroc is not a ... Read More