Synthesis and therapeutic potential of imidazole containing ... | 合法藥品大搜索

由ASiwach著作·2021·被引用1次—Amongthedifferentheterocycliccompounds,imidazoleisbetterknown...Thenitrogenatomonthethirdpositionintheimidazoleringismore ...

Jain et al. [28] synthesized 2-(4-substituted phenyl)-1-substituted-4, 5-diphenyl-1H-imidazole (Scheme 2) and evaluated their antimicrobial activity against S. aureus, E. coli, and B. subtilis by cylinder wells diffusion method using Norfloxacin as a reference drug. Among the different derivatives, compounds 1a and 1b showed good antimicrobial potential. The conclusion of antibacterial activity was presented in (Table 2, Jain et al. [28]).

Synthesis of 2-(4-substitutedphenyl)-1-substituted-4,5-diphenyl-1H-imidazole

Narasimhan et al. [1] synthesized pyridin-3-yl (2-(2,3,4,5-tetra substituted phenyl)-1H-imidazol-1-yl) methanone (Scheme 3). The tube dilution method was used for the determination of antimicrobial potential against S. aureus, B. subtilis, and E. coli using ciprofloxacin as a reference drug. The antifungal activity of these d...