乳癌患者接受化學治療合併靜脈注射甘草甜素之個案報告 | 合法藥品大搜索

林淑娟,黃明立,陳明豐,乳癌,化學治療,肝功能異常,甘草甜素,腫瘤指標CA15-3,Breastcancer,Chemotherapy,Liverdysfunction,Glycyrrhizi,月旦知識庫,整合十大資料庫 ...

The standard treatments of breast cancer are operation, local radiotherapy, systemic chemotherapy and hormone therapy. Regarding chemotherapy for metastatic breast cancer, combination chemotherapy is more effective than single agent. However, most of the drugs used for chemotherapy are metabolized by the liver. Therefore, whether the liver function is tolerable or not becomes the key point for patients receiving systemic chemotherapy. In this report, we present a case of a 43 year old female patient with metastatic breast cancer. She suffered from intolerable liver dysfunction following chemotherapy with intravenous injection of Taxotere and 5FU. Liver function gradually recovered after chemotherapy combined with intravenous injection of glycyrrhiznin (GL) at a dosage of 80mg/day for 2 days pre-chemotherapy and 80mg/day post-chemotherapy. Although liver function improved, the regimen of chemotherapy was changed to another regimen with Taxol and Gemzar due...