Rational design of novel benzisoxazole derivatives with ... | 合法藥品大搜索

1,2-Benzisoxazole is an aromatic organic compound with a molecular formula C7​H5NO containing a benzene-fused isoxazole ring structure. The compound ... Read More

1,2-Benzisoxazole derivative zonisamide is a novel antiepileptic drug and is effective for the treatment of partial seizures. 1,2-Benzisoxazole is a potential ... Read More

由 KP Rakesh 著作 · 2017 · 被引用 36 次 — The benzisoxazole template forms the molecular backbone, possesses versatile binding properties with a frequently occurring binding motif, and provides potent​ ... Read More

1,2-benzoxazole is a benzoxazole in which the benzene ring is fused to a 1,2-​oxazole ring across positions 4 and 5. It is a member of 1,2-benzoxazoles and a ... Read More

It is indicated for the acute treatment and maintenance treatment of schizophrenia and other related psychotic disorders including acute bipolar mania [8–13]. Read More

Zonisamide is a benzisoxazole derivative, first synthesized in 1972, and structurally distinct from other antiepileptic drugs Uno et al (1972). It is believed to exert its ... Read More

由 KP Rakesh 著作 · 2017 · 被引用 36 次 — The benzisoxazole analogs represent one of the privileged structures in medicinal chemistry and there has been an increasing number of studies on ... Read More

An efficient and facile PPh3-mediated Barbier-Grignard-type reaction provides various 3-aryl or alkyl substituted 1,2-benzisoxazoles from 2-​hydroxybenzonitriles ... Read More

由 J Lalut 著作 · 2020 · 被引用 8 次 — Inspired by promising bioactive benzisoxazole compounds, we have conducted a pharmacomodulation study to generate a novel series of ... Read More