Eltrombopag approved as first | 合法藥品大搜索

2018年11月17日—EltrombopagisalsoFDA-approvedforSAApatientswhohavehadaninsufficientresponsetoimmunosuppressivetherapy,forpatientswith ...

Eltrombopag (Promacta)

The U.S. Food and Drug Administration (FDA) has expanded the approved use of eltrombopag (Promacta®) in severe aplastic anemia (SAA).

Eltrombopag is now approved for use in combination with standard immunosuppressive therapy as first-line treatment for adults and pediatric patients age 2 and older with SAA.

Eltrombopag received breakthrough therapy[1] designation and priority review[2] for this indication.

Eltrombopag is also FDA-approved for SAA patients who have had an insufficient response to immunosuppressive therapy, for patients with chronic immune thrombocytopenia who have had an insufficient response to other treatments, and to treat thrombocytopenia in patients with chronic hepatitis C virus infection.

The FDA’s latest approval of eltrombopag is based on results from a phase 1/2 trial (NCT01623167[3]), which were published in The New England Journal of Medicine[4] in April 2017.

Updated results from th...

返利凝25毫克膜衣錠Revolade ™ 25mg film | 合法藥品大搜索

治療ITP 與SAA 患者時，. 對於肝功能不全的患者必須使用較低起始劑量的eltrombopag，並密切進行監測( 請參見. 4.2 章節)。肝臟代償失調( 併用干擾素時). 慢性C 型 ... Read More

Activity of eltrombopag in severe aplastic anemia | 合法藥品大搜索

由 P Scheinberg 著作 · 2018 · 被引用 43 次 — The next steps in development combined eltrombopag with the most active IST regimen in SAA, horse ATG ... Read More

Eltrombopag approved as first | 合法藥品大搜索

2018年11月17日 — Eltrombopag is also FDA-approved for SAA patients who have had an insufficient response to immunosuppressive therapy, for patients with ... Read More

Activity of eltrombopag in severe aplastic anemia | 合法藥品大搜索

How eltrombopag is acting in SAA — The next steps in development combined eltrombopag with the most active IST regimen in SAA, horse ATG ... Read More

Outcome of Standard Immunosuppressive Therapy with or ... | 合法藥品大搜索

由 J JIA 著作 · 2019 · 被引用 1 次 — Eltrombopag is an oral thrombopoietin receptor agonist. In a recent study of newly diagnosed SAA patients, combined standard ... Read More

Promacta (eltrombopag) for the Treatment of Severe Aplastic ... | 合法藥品大搜索

Promacta (eltrombopag) is the first-in-class treatment indicated for patients with severe aplastic anaemia (SAA) immunosuppressive therapy (IST) was proven ... Read More

Current evidence and the emerging role of eltrombopag in ... | 合法藥品大搜索

由 B Drexler 著作 · 2021 — For many decades, the therapy of SAA primarily focused on the immune pathogenesis of the disease, treating patients with either intensive ... Read More

Eltrombopag in children with severe aplastic anemia | 合法藥品大搜索

由 H Lesmana 著作 — The thrombopoietin receptor agonist eltrombopag has been recently approved for SAA patients 2 years and older. However, there are limited ... Read More