VANTA - Clinical: Vancomycin | 合法藥品大搜索

Troughconcentrationsarerecommendedfortherapeuticmonitoringofvancomycin,preferablyacquiredatsteady-state(justbeforefourthdose).Toavoid ...

Preferred test for monitoring vancomycin therapy

Monitoring trough concentrations drawn at steady-state in selected patients receiving vancomycin therapy

Vancomycin is an antibiotic used to treat infections caused by gram-positive organisms that are resistant to beta-lactam antibiotics, such as methicillin-resistant staphylococci (MRSA), Streptococcus viridans group, penicillin/cephalosporin-resistant Streptococcus pneumoniae, and penicillin/ampicillin-resistant Enterococcus species.

The oral formulation, which is not absorbed, is used in the treatment of pseudomembranous colitis caused by Clostridium difficile. Vancomycin is also used when patients are intolerant or allergic to beta-lactam antibiotics.

Vancomycin has been associated with nephrotoxicity and ototoxicity, although it appears that many of these reports reflected impurities in early formulations. Monitoring of vancomycin-related nephrotoxicity is recommended o...