Azilsartan medoxomil | 合法藥品大搜索

由WLBaker著作·2011·被引用68次—AzilsartanmedoxomilisasafeandeffectiveARBwithauniquepharmacologicprofileversusotheragents,includingslowedangiotensinIItype1receptor ...

Objective: To evaluate the efficacy, safety, and clinical role of azilsartan medoxomil, an angiotensin II receptor blocker (ARB) that recently gained Food and Drug Administration approval for lowering of blood pressure (BP) in patients with hypertension.

Data sources: A systematic review of the literature was performed through August 2011 using MEDLINE, Web of Science, and International Pharmaceutical Abstracts and the key words and MeSH terms azilsartan, azilsartan medoxomil, TAK-491, TAK-536, and Edarbi. Abstracts presented in the last 2 years from the annual meetings of appropriate medical societies were reviewed in addition to a search of clinicaltrials.gov.

Study selection and data extraction: Studies eligible for inclusion were in vitro or in vivo evaluations of azilsartan medoxomil, with no restrictions on patient population or indication. Data related to the patient populati...