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Eliminationisrapid,themeanplasmahalf-lifeisbetween1and2hoursandtheclearanceishigh(about1,100ml/min)andessentiallymetabolic.Excretionis ...
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Agomelatine and its therapeutic potential in the depressed ... | 合法藥品大搜索
Profile of agomelatine and its potential in the treatment of ... | 合法藥品大搜索
由 MN Levitan 著作 · 2015 · 被引用 31 次 — Agomelatine is a synthetic naphthalene analog of melatonin and agonist of melatonergic MT1 and MT2 receptors with a longer half-life (mean ... Read More
Agomelatine | 合法藥品大搜索
Agomelatine is an atypical antidepressant used to treat major depressive disorder. One review ... Elimination half-life, 1–2 hours. Excretion · Kidney (80%, mostly ... Read More
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If the drug's half-life is important to you. For example, if you are concerned about withdrawal effects and would prefer a drug with a longer half-life. Read More
Agomelatine | 合法藥品大搜索
由 K Outhoff 著作 · 2012 · 被引用 5 次 — Agomelatine is a novel melatonergic antidepressant that restores disrupted ... Agomelatine has a short half-life of one to two hours, which. Read More
Agomelatine | 合法藥品大搜索
由 B Deakin 著作 · 2009 · 被引用 2 次 — receptor. • It has no antihistamine activity. • It has a very short half-life of about two hours. The implications are that agomela- tine has a novel mechanism of action. Read More
Valdoxan 25 mg film | 合法藥品大搜索
Elimination is rapid, the mean plasma half-life is between 1 and 2 hours and the clearance is high (about 1,100 ml/min) and essentially metabolic. Excretion is ... Read More
Agomelatine | 合法藥品大搜索
由 RT Owen 著作 · 2009 · 被引用 25 次 — It is rapidly absorbed orally and mainly metabolized via CYP1A2 hepatic isoenzymes, has no active metabolites and an elimination half-life of 1-2 hours. Read More
Inhibitory effect of celecoxib on agomelatine metabolism in ... | 合法藥品大搜索
由 J He 著作 · 2018 · 被引用 3 次 — In addition, celecoxib inhibited the metabolism of agomelatine in the in ... Cmax, maximum concentration; t1/2z, terminal elimination half-life; ... Read More
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