Anthracyclines | 合法藥品大搜索

Anthracyclinesareaclassofpotentandwidelyusedcytotoxicdrugs,derivedfromantibioticsthatinhibitDNAandRNAsynthesisbyintercalatingbetweenbase ...

J.K. Aronson MA, DPhil, MBChB, FRCP, HonFBPhS, HonFFPM, in Meylers Side Effects of Drugs, 2016

Cardiovascular

The incidence of cardiotoxicity in anthracycline-treated patients has been related to the peak plasma drug concentration [11,12]. One of the aims in developing pegylated liposomal doxorubicin was to reduce plasma concentrations of free doxorubicin and restrict myocardial penetration, to minimize cardiotoxicity. Preclinical data suggested that the liposomal formulation was indeed less cardiotoxic than the free drug: about 50% more pegylated liposomal doxorubicin than free doxorubicin can be given to rabbits without producing the same frequency of cardiotoxicity [13].

Cardiac adverse events that have been considered probably or possibly related to pegylated liposomal doxorubicin have been reported in 3–9% of p...

Anthracycline 類化療藥物引起的心臟毒性概論 | 合法藥品大搜索

但心肌細胞本身並不是頻繁進行複製的細胞，所以Anthracyclines 造成心. 毒性的機轉似乎與其抗癌作用之機轉不同。 Anthracyclines 中以Doxorubicin 為例，造成心 ... Read More

蒽環類藥物 | 合法藥品大搜索

蒽環類藥物（英語：Anthracyclines）或蒽環類抗生素（英語：Anthracycline antibiotics）是一類來源於波賽鏈黴菌青灰變種（Streptomyces peucetius var. Read More

Anthracycline | 合法藥品大搜索

Anthracyclines is a class of drugs used in cancer chemotherapy that are extracted from Streptomyces bacterium. ... These compounds are used to treat many ... Read More

化學藥物治療中的心臟保護劑Dexrazoxane | 合法藥品大搜索

使用Anthracyclines類化學藥品治療的癌症病人，因該類藥品有其毒性，如累積用藥量過多，常引起鬱血性心臟衰竭(congestive heart failure)，而Dexrazoxane 可緩解 ... Read More

Anthracyclines | 合法藥品大搜索

由 P Venkatesh 著作 · 2020 · 被引用 6 次 — Anthracyclines have a chromophore moiety that has an intercalating function and inserts between adjacent base pairs of DNA when localized to ... Read More

Anthracyclines | 合法藥品大搜索

Anthracyclines are a class of potent and widely used cytotoxic drugs, derived from antibiotics that inhibit DNA and RNA synthesis by intercalating between base ... Read More

Anthracyclines | 合法藥品大搜索

The clinical use of anthracyclines like doxorubicin and daunorubicin can be viewed as a sort of double-edged sword. On the one hand, anthracyclines play an ... Read More

Anthracyclines in the treatment of cancer. An overview | 合法藥品大搜索

由 GN Hortobágyi 著作 · 1997 · 被引用 797 次 — Anthracyclines are widely used and effective antineoplastic drugs. Although active against a wide variety of solid tumours and haematological malignancies, ... Read More

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