Is there a role for prazosin in the treatment of post ... | 合法藥品大搜索

ThetreatmentofPTSDischallenging,fre-quentlyrequiringspecialistinputfrompsychiatrists.Prazosinhasbeenproventobesafeandeffectiveinthe ...

Introduction This article is the next in our series of occasional papers ‘At the cutting edge’, where we invite researchers to inform readers on where they believe clinical practice is heading. The material published in this article is not mainstream or part of standard clinical practice. However, we hope readers will be inspired and enjoy contemplating where clinical medicine may lead in the future – the Editor.

Background Post-traumatic stress disorder (PTSD) is a common disorder with significant morbidity and associated comorbidities, including mood disorders and substance abuse, and is frequently misdiagnosed or under-diagnosed. Management of PTSD requires combined psychotherapy and pharmacotherapy, but some symptoms, particularly nightmares and sleep disturbance, are often resistant to treatment.

Objective The aim of this article is to inform primary healthcare professionals of the prevalence and significance of PTSD, and to review the evidence that prazosin is a u...