Design of new oxazaphosphorine anticancer drugs | 合法藥品大搜索

Oxazaphosphorine 類藥物和Mesna 的比例應維持不變。 副作用：. 有少部份與器官有關之過敏反應的例子，如不同程度的皮膚與黏膜反應(癢、 發紅、 水泡)、 ... Read More

藥理作用. Mesna是含SH基團之化合物，由於與Oxazaphosphorine之反應性代謝產物鍵結而防止尿道黏膜之傷害，排泄速率比Oxazaphoshporine及其代謝產物快。 Read More

在這些情況下，使⽤硫醇化合物時需要特別注意。 Mesna 預防出血性膀胱炎並非對所有患者都有用，因此，應據此監測患者。如同與任何Oxazaphosphorine 類藥物. Read More

The oxazaphosphorine cyclophosphamide is one of the most widely used drugs in cancer chemotherapy. It is also used as an immunosuppressive at lower doses​. Read More

由 B Giraud 著作 · 2010 · 被引用 82 次 — Areas covered in this review: This review highlights potential strategies for limiting side effects commonly associated with the oxazaphosphorine drugs, through ... Read More

由 J Liang 著作 · 2007 · 被引用 43 次 — The oxazaphosphorines including cyclophosphamide (CPA, Cytoxan, or Neosar)​, ifosfamide (IFO, Ifex) and trofosfamide (Ixoten) represent an important group of ... Read More

由 J Zhang 著作 · 2005 · 被引用 199 次 — Oxazaphosphorine metabolism is affected by a number of factors associated with the drugs (e.g., dosage, route of administration, chirality, and drug combination) ... Read More

由 N Brock 著作 · 1982 · 被引用 161 次 — Studies on the urotoxicity of oxazaphosphorine cytostatics and its prevention--III. Profile of action of sodium 2-mercaptoethane sulfonate (mesna). Eur J Cancer ... Read More