Trifluridinetipiracil versus placebo in patients with heavily ... | 合法藥品大搜索

商品名, lonsurf ☆15mg(低劑量)(需事審), 藥品許可證, 衛部藥輸字第027281號. 中文名, 朗斯弗膜衣錠, 健保局藥理類別, 100000 抗癌藥物. 學名, Trifluridine+​Tipiracil ... Read More

Trifluridine是胸腺嘧啶基底的核苷類似物，進入癌細胞後會直接嵌入DNA並干擾DNA 合成及抑制癌細胞增生；tipiracil為thymidine phosphorylase 抑制劑，可以抑制 ... Read More

Tipiracil is a thymidine phosphorylase (TPase) inhibitor and inhibits degradation of trifluridine by inhibiting TPase, thus increasing systemic exposure to trifluridine​ ... Read More

由 CB Burness 著作 · 2016 · 被引用 44 次 — Trifluridine/tipiracil (Lonsurf(®)) is a novel, orally active, antimetabolite agent comprised of trifluridine, a thymidine-based nucleoside analogue, and tipiracil, ... Read More

由 K Shitara 著作 · 2018 · 被引用 182 次 — Trifluridine/tipiracil versus placebo in patients with heavily pretreated metastatic gastric cancer (TAGS): a randomised, double-blind, placebo-controlled, phase 3​ ... Read More

Tipiracil is a thymidine phosphorylase inhibitor. It is used in combination with trifluridine, in a ratio of 1:0.5, to form TAS-102. The main function of Tipiracil in TAS- ... Read More

Why is this medication prescribed? ... The combination of trifluridine and tipiracil is used to treat colon (large intestine) or rectal cancer that has spread to other parts ... Read More

Active substance. trifluridine; tipiracil hydrochloride. International non-proprietary name (INN) or common name. trifluridine; tipiracil. Therapeutic area (MeSH). Read More

2016年4月25日 — Lonsurf 20 mg/8.19 mg film-coated tablets. Each film-coated tablet contains 20 mg trifluridine and 8.19 mg tipiracil (as hydrochloride). Excipient ... Read More