Panitumumab | 合法藥品大搜索

Panitumumab(INN),formerlyABX-EGF,isafullyhumanmonoclonalantibodyspecifictotheepidermalgrowthfactorreceptor(alsoknownasEGFreceptor, ...

Pharmaceutical drug

Panitumumab, sold under the brand name Vectibix, is a fully human monoclonal antibody specific to the epidermal growth factor receptor (also known as EGF receptor, EGFR, ErbB-1 and HER1 in humans).[1][2]

Panitumumab is manufactured by Amgen and was originally developed by Abgenix Inc.

In 2014, Amgen and Illumina entered into an agreement to develop a companion diagnostic to accompany panitumumab.[3]

Medical uses[edit]

Panitumumab was approved by the U.S. Food and Drug Administration (FDA) for the first time in September 2006, for "the treatment of EGFR-expressing metastatic colorectal cancer with disease progression" despite prior treatment.[4] Panitumumab was approved by the European Medicines Agency (EMEA) in 2007, and by Health Canada in 2008, for "the treatment of refractory EGFR-expressing metastatic colorectal cancer in ...

Panitumumab | 合法藥品大搜索

Panitumumab (INN), formerly ABX-EGF, is a fully human monoclonal antibody specific to the epidermal growth factor receptor (also known as EGF receptor, ... Read More

Cetuximab | 合法藥品大搜索

Cetuximab is an epidermal growth factor receptor (EGFR) inhibitor medication used for the ... KRAS, since it had little or no effect in colorectal tumors harboring a KRAS mutation (this also applied to the EGFR antibody panitumumab). Read More

Vectibix® (panitumumab) for Metastatic Colorectal Cancer | 合法藥品大搜索

Vectibix® (panitumumab) is for treating patients with wild-type RAS metastatic colorectal cancer (cancer that has spread outside of the colon and rectum). RAS ... Read More

Panitumumab (Vectibix) | 合法藥品大搜索

Class/mechanism: EGFR antagonist; recombinant human IgG2 kappa monoclonal antibody that binds to EGFR (human epidermal growth factor receptor), ... Read More

Panitumumab – Wikipedia | 合法藥品大搜索

Panitumumab (Handelsname Vectibix; Hersteller Amgen) ist ein humaner monoklonaler Antikörper aus der Gruppe der Immunglobuline IgG2κ. Er bindet an den ... Read More

panitumumab | 合法藥品大搜索

panitumumab的中文名为帕尼单抗，是一种结直肠癌治疗药。 ... 2014年5月23日，FDA已批准Vectibix（帕尼单抗，panitumumab）联合FOLFOX（一种基于奥沙利 ... Read More

晚期大腸直腸癌新藥panitumumab (Vectibix®) | 合法藥品大搜索

Vectibix®學名為panitumumab，為基因重組的全人類IgG2單株抗體，可與EGFR形成高親和力及專一性的結合，抑制所有已知由EGFR誘發的受體自動磷酸化作用。 Read More

卡瑞利珠單抗 | 合法藥品大搜索

卡瑞利珠單抗[編輯] ... 卡瑞利珠單抗（Camrelizumab，研發代號SHR-1210，商品名艾瑞卡）（ INN ）是一種抗PD-1免疫檢查點抑制劑，正在針對肝細胞癌的適應症 ... Read More

Panitumumab — Wikipédia | 合法藥品大搜索

Panitumumab est un anticorps monoclonal thérapeutique ciblant le récepteur EGFR. Articles connexes[modifier | modifier le code]. Liste d'anticorps monoclonaux ... Read More