Ketoprofen 2.5% gel | 合法藥品大搜索

Ketoprofen(KP),anonsteroidalanti-inflammatorydrug(NSAID),possessesanalgesic,antipyreticandanti-inflammatoryproperties.OralKPiswidelyusedin ...

Ketoprofen (KP), a nonsteroidal anti-inflammatory drug (NSAID), possesses analgesic, antipyretic and anti-inflammatory properties. Oral KP is widely used in musculoskeletal pain and inflammation in muscles and joints, including arthritis pain, osteoarthritis, stiffness of the joints, soft tissue rheumatism, and sports injuries. In common with all NSAIDs, oral KP has been associated with systemic adverse events and in particular gastrointestinal disorders. Topical application of the active ingredient is locally effective and at the same time minimises the risk of systemic adverse events. Pharmacokinetic studies show that serum levels of the active ingredient following topical KP 2.5% gel are less than 1% of those reported after oral dosing, thereby providing good levels of pain relief without the systemic adverse events normally associated with oral NSAIDs. In comparative studies, topical KP 2.5% gel twice daily show...