Drug interaction | 合法藥品大搜索

Acauseofadruginteractioninvolvesonedrugwhichaltersthepharmacokineticsofanothermedicaldrug.Alternatively,druginteractionsresultfrom ...

Change in the action or side effects of a drug caused

In pharmaceutical sciences, drug interactions occur when a drugs mechanism of action is affected by the concomitant administration of substances such as foods, beverages, or other drugs. A popular example of drug–food interaction is the effect of grapefruit on the metabolism of drugs.

Interactions may occur by simultaneous targeting of receptors, directly or indirectly. For example, both Zolpidem and alcohol affect GABAA receptors, and their simultaneous consumption results in the overstimulation of the receptor, which can lead to loss of consciousness. When two drugs affect each other, it is a drug–drug interaction (DDI). The risk of a DDI increases with the number of drugs used.[1]

A large share of elderly people regularly use five or more medications or supplements, with a significant risk of side-effects from drug–drug inte...