Managing Rasburicase | 合法藥品大搜索

對尿酸酵素或製劑中的成份過敏者、G6PD 缺乏症或其他已知會造成溶血性貧血、或變性血紅素血症的病 人。 對Allopurinol過敏者. 臨床療效. Andre Bosly等人根據1999到2001年 ... Read More

由 M Akande 著作 · 2017 · 被引用 5 次 — Despite its proven safety and effectiveness, rasburicase is contra-indicated in patients with known glucose-6-phosphate dehydrogenase (G6PD) deficiency as it ... Read More

由 L Dean 著作 · 2020 · 被引用 1 次 — Rasburicase is contraindicated in individuals with G6PD deficiency. The FDA-approved drug label states that individuals at higher risk for G6PD ... Read More

由 AP Nguyen 著作 · 2014 · 被引用 14 次 — Rasburicase is approved for use in the prevention and treatment of TLS in patients receiving chemotherapy. It is contraindicated in patients with a G6PD ... Read More

由 MV Relling 著作 · 2014 · 被引用 88 次 — Rasburicase is contraindicated in G6PD‐deficient patients due to the risk of AHA and possibly methemoglobinemia. Unless preemptive genotyping has established a ... Read More

2018年11月28日 — The drug rasburicase is used to combat hyperuricemia, excess uric acid buildup in the blood as a result of tumor cell death. However, ... Read More

由 MA Borg 著作 · 被引用 1 次 — After rasburicase administration, in patients with G6PD deficiency, hemolysis may occur intravascularly, in which hemoglobin is being released into the blood ... Read More

因為Rasburicase將尿酸氧化成allantoin的過程中，會出現過氧化氫（H2O2）的副產物，因此G6PD缺乏患者禁止使用此藥品，以避免引起嚴重溶血反應。此外，對於rasburicase ... Read More

由 D Ferguson 著作 · 2018 · 被引用 5 次 — Rasburicase-induced hemolytic anemia in previously undiagnosed G6PD deficiency. Blood. 2018 Aug 9;132(6):673. doi: 10.1182/blood-2018-04-842724. Read More

由 M Khan 著作 · 2017 · 被引用 15 次 — Methemoglobinemia is a serious rare adverse effect of rasburicase, more common in patients with G6PD deficiency. Prompt diagnosis and appropriate management ... Read More