Sensipar (cinacalcet) | 合法藥品大搜索

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由 CA Byrnes 著作 · 2005 · 被引用 15 次 — Cinacalcet's mechanism of action decreases parathyroid hormone, calcium, and phosphorus levels, offering potential advantages over the other treatments for ... Read More

由 JAB Balfour 著作 · 2005 · 被引用 66 次 — Oral cinacalcet hydrochloride (HCl) [Sensipar, Mimpara] is the first in a new class of therapeutic agents, the calcimimetics, and has a novel mechanism of ... Read More

由 K Yokoyama 著作 · 2015 · 被引用 1 次 — Cinacalcet acts on calcium receptors (CaR) expressed on chief cells of the parathyroid gland to inhibit the secretion of parathyroid hormone (PTH) . Read More

由 P Ureña 著作 · 2005 · 被引用 2 次 — [Calcimimetics, mechanisms of action and therapeutic applications] ... Calcium / agonists*; Cells, Cultured; Cinacalcet; Double-Blind Method ... Read More

Mechanism of action — Mechanism of action[edit]. Cinacalcet is a drug that acts as a calcimimetic (i.e. it mimics the action of ... Read More

Mechanism of Action · 由 Z Junaid 著作 · 2020 — Identify the mechanism of action of cinacalcet. Describe the possible adverse effects of cinacalcet. Review the appropriate monitoring ... Read More

由 G Poon 著作 · 2005 · 被引用 30 次 — Cinacalcet is a type II calcimimetic agent with a novel medianism of action (7, 11). It binds to the transmembrane region of the calcium-sensing receptor, which ... Read More

Cinacalcet binds to the transmembrane domain of the G-protein-coupled calcium sensing receptor (CaSR) on the parathyroid cells, producing allosteric activation ... Read More

Mechanism of Action ... Cinacalcet is an oral calcimimetic agent that increases the sensitivity of the calcium-sensing receptor to activation by extracellular ... Read More