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Mechanism of Action · 由 J Nakashima 著作 · 2020 · 被引用 2 次 — The exact mechanism of mesalamine is unknown. · Depending on the formulation of the drug, mesalamine can get released at different ... Read More

由 R Karagozian 著作 · 2007 · 被引用 64 次 — A variety of different mechanisms have been proposed by which aminosalicylates work in inflammatory bowel disease. The main mechanism includes the inhibition of ... Read More

DELIVERY MECHANISMS · 由 B Ye 著作 · 2015 · 被引用 64 次 — However, the exact mechanism of action of mesalazine remains poorly elucidated. It is believed to exert a negative effect on the ... Read More

Although the mechanism of action of mesalazine is not fully understood, it is believed to possess a topical anti-inflammatory effect on colonic epithelial ... Read More

由 H Allgayer 著作 · 2003 · 被引用 123 次 — Review article: mechanisms of action of mesalazine in preventing colorectal carcinoma in inflammatory bowel disease ... Aliment Pharmacol Ther. 2003 Sep;18 Suppl ... Read More

Chemistry[edit] ... Mesalazine is the active moiety of sulfasalazine, which is metabolized to sulfapyridine and mesalazine. ... It is also the active component of ... Read More

由 H Allgayer 著作 · 2003 · 被引用 123 次 — It has also been shown that mesalazine inhibits TNFα-mediated effects on intestinal cell proliferation and activation of MAP kinase and NFκB. Read More

The mechanism by which mesalamine acts during the treatment of inflammatory bowel disease remains unknown, but this drug is believed to work through ... Read More