Regulation of plasminogen activation on cell surfaces and fibrin | 合法藥品大搜索

2014年6月4日 — 血栓（blood clot）是凝血酶（thrombin）/血纖維蛋白（fibrin）凝血機制所造成的：凝血酶將溶於血漿中的血纖維蛋白酶原（fibrinogen）轉換成不溶於 ... Read More

Plasmin is an important enzyme (EC 3.4.21.7) present in blood that degrades many blood plasma proteins, including fibrin clots. The degradation of fibrin is ... Read More

由 JC Chapin 著作 · 2015 · 被引用 495 次 — Plasmin is generated from the zymogen plasminogen on the surface of the fibrin clot, or on cell surfaces, by either tissue plasminogen ... Read More

由 T Urano 著作 · 2018 · 被引用 56 次 — The primary role of the fibrinolytic system is to dissolve fibrin‐containing thrombi by the major extracellular protease plasmin (plm), in order to maintain ... Read More

Tissue plasminogen activator (tPA) converts plasminogen into plasmin, then plasmin will dissolve the ... Read More

由 E Suenson 著作 · 1984 · 被引用 329 次 — This study deals with the effect of fibrin on the transformation of Glu-plasminogen to Glu-plasmin during fibrinolysis. Read More

由 MC Drinane 著作 · 2006 · 被引用 28 次 — Objective: While coronary artery disease (CAD) is associated with disturbances of the plasma fibrinolytic system, the nature of these disturbances is not ... Read More

由 ME Carr Jr 著作 · 1995 · 被引用 181 次 — Previous studies in purified systems have demonstrated that fibrin structure influences the rate of conversion of plasminogen to plasmin by t-PA as well as ... Read More

由 C Thelwell 著作 · 2007 · 被引用 59 次 — Fibrinogen and fibrin modulate the activity of tPA differently in regard to their activation of plasminogen and inhibition by PAI-1. Fibrinogen and fibrin ... Read More