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Modified FOLFIRINOX in pancreatic cancer patients Age 75 or ... | 合法藥品大搜索

Modified FOLFIRINOX in pancreatic cancer patients Age 75 or ...

由JDMizrahi著作·2020·被引用16次—Background:AlthoughFOLFIRINOX(5-Fluorouracil+leucovorin+irinotecan+oxaliplatin)isnowthestandardofcareforpatients(pts)withmetastatic ...

 Modified FOLFIRINOX in pancreatic cancer patients Age 75 or ...

Background: Although FOLFIRINOX (5-Fluorouracil + leucovorin + irinotecan + oxaliplatin) is now the standard of care for patients (pts) with metastatic pancreatic cancer (PC) based on the 2011 study by Conroy et al. which demonstrated improved median overall survival (mOS), pts > 75 yrs old were excluded from this study. The purpose of this study was to assess the safety and efficacy of modified FOLFIRINOX (mFOLFIRINOX) in this population.

Methods: We retrospectively analyzed unresectable PC pts, age ≥ 75, treated with mFOLFIRINOX at MD Anderson from 2011 to 2017. Primary outcome was rate of grade 3 or 4 hematologic toxicity (HT).

Results: 24 pts were included. Grade 3 or ...

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Modified FOLFIRINOX for resected pancreatic cancer ... | 合法藥品大搜索
由 F Yang 著作 · 2019 · 被引用 4 次 — The modified FOLFIRINOX regimen is superior to gemcitabine as adjuvant therapy for resected pancreatic cancer, and should be a new standard of care for this ... Read More
Modified FOLFIRINOX for unresectable locally advanced ... | 合法藥品大搜索
由 L Cavanna 著作 · 2019 · 被引用 8 次 — Purpose: Metastatic pancreatic adenocarcinoma has a very poor prognosis. Although irinotecan, oxaliplatin and leucovorin-modulated ... Read More
Modified FOLFIRINOX for pancreatic cancer | 合法藥品大搜索
Dilute in 500 to 1000 mL 0.9% NS or D5W¶ and administer as a continuous IV infusion over 46 hours. To accommodate an ambulatory pump for outpatient treatment, ... Read More
Modified FOLFIRINOX chemotherapy for pancreatic cancer [1 | 合法藥品大搜索
Bookmark. Tools. © 2021 UpToDate, Inc. and/or its affiliates. All Rights Reserved. Modified FOLFIRINOX chemotherapy for pancreatic cancer ... Read More
The benefits of modified FOLFIRINOX for advanced pancreatic ... | 合法藥品大搜索
由 H Tong 著作 · 2018 · 被引用 35 次 — In general, the modified FOLFIRINOX regimen could provide good survival benefits for patients with advanced pancreatic cancer by increasing the ... Read More
Modified | 合法藥品大搜索
由 X Li 著作 · 2017 · 被引用 32 次 — FOLFIRINOX chemotherapy has shown remarkable responses in patients with metastatic pancreatic cancer (MPC), and has significantly improved ... Read More
Modified FOLFIRINOX in pancreatic cancer patients Age 75 or ... | 合法藥品大搜索
由 JD Mizrahi 著作 · 2020 · 被引用 16 次 — Background: Although FOLFIRINOX (5-Fluorouracil + leucovorin + irinotecan + oxaliplatin) is now the standard of care for patients (pts) with metastatic ... Read More
FOLFIRINOX or Gemcitabine as Adjuvant Therapy for ... | 合法藥品大搜索
由 T Conroy 著作 · 2018 · 被引用 881 次 — Conclusions. Adjuvant therapy with a modified FOLFIRINOX regimen led to significantly longer survival than gemcitabine among patients with ... Read More
Study of Modified FOLFIRINOX in Advanced Pancreatic ... | 合法藥品大搜索
Patients with metastatic pancreatic cancer (MPC) were treated with modified FOLFIRINOX every 2 weeks as follows: oxaliplatin 85 mg m 2 infused over 120 min, ... Read More
ASCO Guideline Update | 合法藥品大搜索
2019年6月18日 — ASCO Guideline Update: Modified FOLFIRINOX Is Preferred as Adjuvant Chemotherapy in Patients With Resected Pancreatic Adenocarcinoma · Get Cancer ... Read More
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