Differences in cardiotoxicity of bupivacaine and ropivacaine ... | 合法藥品大搜索

由 P Dony 著作 · 2000 · 被引用 221 次 — In the bupivacaine group, two animals required cardiopulmonary resuscitation before any seizure activity could be detected, and only three rats survived. We ... Read More

由 DB Scott 著作 · 1989 · 被引用 1126 次 — The acute central nervous and cardiovascular effects of the local anesthetics ropivacaine and bupivacaine were compared in 12 volunteers in a randomized ... Read More

由 W Zink 著作 · 2008 · 被引用 185 次 — Purpose of review: Ropivacaine and levobupivacaine were developed after evidence of bupivacaine-related severe toxicity. Despite a comparable analgesic ... Read More

由 SL Piper 著作 · 2008 · 被引用 263 次 — In vitro, 0.5% ropivacaine is significantly less toxic than 0.5% bupivacaine in both intact human articular cartilage and chondrocyte culture. Read More

由 AC Santos 著作 · 1995 · 被引用 193 次 — In pregnant ewes, greater doses of ropivacaine as compared to bupivacaine were required to produce convulsions (7.5 +/- 0.5 vs. 5.0 +/- 0.6 mg.kg-1) and ... Read More

由 BM Graf 著作 · 2002 · 被引用 197 次 — The aim of this study was to compare the direct cardiac effects of the optically pure S(-)-ropivacaine isomer and its nonclinically used R(+)-isomer with both ... Read More

由 AC Santos 著作 · 2001 · 被引用 201 次 — Systemic toxicity of levobupivacaine, bupivacaine, and ropivacaine during continuous intravenous infusion to nonpregnant and pregnant ewes. Anesthesiology. 2001 ... Read More