Mycamine (Micafungin Sodium): Uses | 合法藥品大搜索

Eachsingle-usevialcontains50mgor100mgmicafunginsodium,200mglactose,withcitricacidand/orsodiumhydroxide(usedforpHadjustment).Mycamine ...

Micafungin is a member of the echinocandin class of antifungal agents [see Microbiology].

The pharmacodynamics of micafungin related to hematogenous Candida meningoencephalitis are described in other sections of the prescribing information [see Use In Specific Populations  and Microbiology].

The pharmacokinetics of micafungin were determined in healthy subjects, hematopoietic stem cell transplant recipients, and patients with esophageal candidiasis up to a maximum daily dose of 8 mg/kg body weight.

The relationship of area under the concentration-time curve (AUC) to micafungin dose was linear over the daily dose range of 50 mg to 150 mg and 3 mg/kg to 8 mg/kg body weight. Typically, 85% of the steady-state concentration is achieved after three daily MYCAMINE doses.

Steady-state pharmacokinetic parameters in relevant ...