Lenvatinib Versus Sorafenib as First | 合法藥品大搜索

由JJKim著作·被引用13次—Recently,lenvatinibbecamethefirstagentinmorethan10yearstoreceiveapprovalasfirst-linetherapyforunresectableHCC,alongwiththe ...

Background: In a global, phase III, open-label, noninferiority trial (REFLECT), lenvatinib demonstrated noninferiority to sorafenib in overall survival and a statistically significant increase in progression-free survival in patients with unresectable hepatocellular carcinoma (HCC). Recently, lenvatinib became the first agent in more than 10 years to receive approval as first-line therapy for unresectable HCC, along with the previously approved sorafenib. The objective of this study was to determine the comparative cost-effectiveness of lenvatinib and sorafenib as a first-line therapy of unresectable HCC.

Materials and methods: A state-transition model of unresectable HCC was developed in the form of a cost-utility analysis. The model time horizon was 5 years; the efficacy of the mode...

Lenvatinib versus sorafenib in first | 合法藥品大搜索

由 M Kudo 著作 · 2018 · 被引用 1767 次 — Methods: This was an open-label, phase 3, multicentre, non-inferiority trial that recruited patients with unresectable hepatocellular carcinoma, ... Read More

Lenvatinib | 合法藥品大搜索

由 ZT Al-Salama 著作 · 2019 · 被引用 28 次 — Lenvatinib (Lenvima®) is an oral small molecule inhibitor of multiple receptor tyrosine kinases, and is approved for the first-line treatment of patients ... Read More

Lenvatinib Versus Sorafenib as First | 合法藥品大搜索

由 JJ Kim 著作 · 被引用 13 次 — Recently, lenvatinib became the first agent in more than 10 years to receive approval as first-line therapy for unresectable HCC, along with the ... Read More

Lenvatinib versus sorafenib in first | 合法藥品大搜索

由 M Kudo 著作 · 2018 · 被引用 1767 次 — Lenvatinib was non-inferior to sorafenib in overall survival in untreated advanced hepatocellular carcinoma. The safety and tolerability ... Read More

Lenvatinib for the treatment of unresectable hepatocellular ... | 合法藥品大搜索

由 N Personeni 著作 · 2019 · 被引用 32 次 — Lenvatinib for first-line treatment of HCC ... Lenvatinib is an oral multikinase inhibitor that inhibits vascular endothelial growth factor (VEGF) ... Read More

Lenvatinib versus sorafenib in hepatocellular carcinoma | 合法藥品大搜索

由 A Dipasquale 著作 · 2021 · 被引用 1 次 — Lenvatinib versus sorafenib in the first-line treatment of unresectable hepatocellular carcinoma-new therapeutic scenario. Read More

Real | 合法藥品大搜索

由 J Cheon 著作 · 2020 · 被引用 11 次 — Current international guidelines recommend lenvatinib as the first-line therapy for patients with advanced HCC [12-15]. Real-world evidence is important in HCC ... Read More

Lenvatinib Effective as First Line Therapy for Patients with ... | 合法藥品大搜索

2021年1月17日 — Lenvatinib Effective as First Line Therapy for Patients with Hepatocellular Carcinoma ... Lenvatinib monotherapy was an effective first-line ... Read More

Lenvatinib製劑 | 合法藥品大搜索

在治療RCC的Study 205、治療HCC的REFLECT試驗與治療DTC的. SELECT試驗中，接受Lenvima®或Lenvima®併用everolimus治療之病. 人，分別有2%、2%及5%發生動脈血管栓塞，在所有 ... Read More

Lenvatinib for Hepatocellular Carcinoma | 合法藥品大搜索

由 T Hatanaka 著作 · 2021 — Hepatocellular carcinoma (HCC) is the most frequent type of primary liver cancer, which accounts for approximately 80% of all cases [1]. Read More

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