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Fosaprepitant | 合法藥品大搜索

Fosaprepitant

Fosaprepitantisanantiemeticmedication,administeredintravenously....Drugs.com,FDAApprovesEmend(fosaprepitantdimeglumine)forInjection, ...

 Fosaprepitant

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Chemical compound

FosaprepitantTrade namesEmend, IvemendAHFS/Drugs.comMicromedex Detailed Consumer InformationMedlinePlusa604003License data PregnancycategoryRoutes ofadministrationIntravenousATC codeLegal status Bioavailabilityn/aProtein binding>95% (aprepitant)MetabolismTo aprepitantElimination half-life9 to 13 hours (aprepitant)

[3-{[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl] ethoxy]-3-(4-fluorophenyl)morpholin-4-yl]methyl}-5-oxo- 2H-1,2,4-triazol-1-yl]phosphonic acid

CAS NumberPubChem CIDIUPHAR/BPSDrugBankChemSpiderUNIIKEGGChEBIChEMBLCompTox Dashboard (EPA)FormulaC23H22F7N4O6PMolar mass614.414 g·mol−13D model (JSmol)

C[C@H](c1cc(cc(c1)C(F)(F)F)C(F)(F)F)O[C@@H]2[C@@H](N(CCO2)Cc3[nH]c(=O)n(n3)P(=O)(O)O)c4ccc(cc4)F

InChI=1S/C23H22F7N4O6P/c1-12(14-8-15(22(25,26)27)10-16(9-14)23(28,29)30)40-20-19(13-2-4-17(24)5-3-13)33(6-7-39-20)11-18-31-21(35)34(32-18)41(36,37)38/h2-5,8-10,12,19-20H,6-7,...

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Fosaprepitant Dimeglumine | 合法藥品大搜索
由 KP Garnock-Jones 著作 · 2016 · 被引用 4 次 — Intravenous fosaprepitant dimeglumine (Emend(®) for injection, IVEmend(®); henceforth referred to as fosaprepitant) is a prodrug of and is rapidly converted ... Read More
Fosaprepitant dimeglumine for the management of ... | 合法藥品大搜索
由 N Candelario 著作 · 2016 · 被引用 6 次 — Chemotherapy-induced nausea and vomiting (CINV) is a debilitating side effect of antineoplastic agents. Several treatment regimens are used ... Read More
Pharmacokinetic evaluation of fosaprepitant dimeglumine | 合法藥品大搜索
由 F Colon-Gonzalez 著作 · 2010 · 被引用 25 次 — Fosaprepitant is an intravenous prodrug of aprepitant that offers a new alternative to patients with CINV. Currently, fosaprepitant can substitute oral ... Read More
Definition of fosaprepitant dimeglumine | 合法藥品大搜索
A drug used together with other drugs to prevent and control nausea and vomiting caused by cancer treatment. It is given in a vein. It is a type of antiemetic ... Read More
Fosaprepitant dimeglumine | 合法藥品大搜索
Fosaprepitant dimeglumine is an organoammonium salt obtained by reaction of fosaprepitant with two equivalents of 1-deoxy-1-(methylamino)-D-glucitol. A ... Read More
Emend Injection (Fosaprepitant Dimeglumine Injection) | 合法藥品大搜索
Fosaprepitant dimeglumine is a white to off-white amorphous powder with a molecular weight of 1004.83. It is freely soluble in water. Read More
IVEMEND, INN | 合法藥品大搜索
IVEMEND 150 mg powder for solution for infusion. 2. QUALITATIVE AND QUANTITATIVE COMPOSITION. Each vial contains fosaprepitant dimeglumine equivalent to 150 mg ... Read More
Fosaprepitant dimeglumine for the management of ... | 合法藥品大搜索
由 N Candelario 著作 · 2016 · 被引用 6 次 — Fosaprepitant is a neurokinin-1 receptor blocker used in the prevention and treatment of CINV, especially for moderately and severely emetogenic ... Read More
IVEMEND | 合法藥品大搜索
Each vial contains fosaprepitant dimeglumine equivalent to 150 mg fosaprepitant, which corresponds to 130.5 mg of aprepitant. Read More
Fosaprepitant | 合法藥品大搜索
Fosaprepitant is an antiemetic medication, administered intravenously. ... Drugs.com, FDA Approves Emend (fosaprepitant dimeglumine) for Injection, ... Read More
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