Bumetanide 之肌肉骨骼不良反應／李宜汶、葉子慧 ... | 合法藥品大搜索

Three Cases of Severe Bumetanide-Associated Musculoskeletal Reaction

Yi-Wen Li, Zi-Hui Yeh, Shu-Hui Sun Department of Pharmacy, Far Eastern Memorial Hospital

Abstract

Diuretics are usually used to treat edema and oliguria in patients with heart or renal failure. Bumetanide is 40-fold more potent than furosemide, and can be used in patients with poor response to furosemide or furosemide allergy. There are literatures revealed that continuous infusion is more effective than intermittent administration when giving the same dose of the same drug; therefore, continuous infusion of bumetanide is often chosen over intermittent administration to increase urine output and decrease the negative impacts of fluid overload. Severe musculoskeletal reactions associated with bumetanide have been ...