Sitagliptinmetformin | 合法藥品大搜索

Sitagliptin/metformin,soldunderthebrandnameJanumetamongothers,isafixed-dosecombinationanti-diabeticmedicationusedtotreattype2diabetes.

Pharmaceutical drug

Sitagliptin/metformin, sold under the brand name Janumet among others, is a fixed-dose combination anti-diabetic medication used to treat type 2 diabetes.[9] It may be used in those whose blood sugar is not controlled with metformin and a sulfonylurea.[9][10] It is taken by mouth.[9]

Common side effects include diarrhea, headache, and upper respiratory tract infections.[5] Serious side effects may include lactic acidosis, pancreatitis, low blood sugar, heart failure, joint pain, and allergic reactions.[5] It has not been properly studied in women who are pregnant or breastfeeding.[1] It contains sitagliptin (a dipeptidyl peptidase-4 inhibitor) and metformin (a biguanide).[5]

The combination was approved for medical use in the United States in 2007.[5] In 2021, it was the 154th most commonly prescribed medication in the United States, with more than 3 million prescriptions.[11][12] It is available as a generic medication.[13][14]

In the...