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Melphalan: Uses | 合法藥品大搜索

Melphalan: Uses

MelphalanattachesalkylgroupstotheN-7positionofguanineandN-3positionofadenine,leadingtotheformationofmonoadducts,andDNAfragmentingwhen ...

 Melphalan: Uses

Melphalan attaches alkyl groups to the N-7 position of guanine and N-3 position of adenine, leading to the formation of monoadducts, and DNA fragmenting when ...

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Melphalan | 合法藥品大搜索
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Melphalan: Uses | 合法藥品大搜索
Melphalan attaches alkyl groups to the N-7 position of guanine and N-3 position of adenine, leading to the formation of monoadducts, and DNA fragmenting when ... Read More
Melphalan flufenamide: Uses | 合法藥品大搜索
2021年2月28日 — Melphalan flufenamide is a melphalan prodrug used to treat relapsed or refractory multiple myeloma. ... Mechanism of action. Melphalan ... Read More
MELPHALAN | 合法藥品大搜索
2012 — 4.2.1 Induction of DNA damage · Melphalan is a direct-acting, bifunctional alkylating agent that binds to cellular macromolecules (Osborne et al., 1995). · Melphalan ... Read More
Melphalan | 合法藥品大搜索
Mechanism of action. Melphalan is a member of the nitrogen mustard alkylating agent family. Melphalan alkylates guanine, which results in inter- and intrastrand ... Read More
Mechanism of Melphalan Resistance Developed in Vitro in ... | 合法藥品大搜索
由 PG Parsons 著作 · 1981 · 被引用 88 次 — Molecular mechanisms of the cytotoxic action of difunctional alkylating agents and of resistance to this action. Nature. (Lond.), 208. 480-483. 1965. 29. Lehmann, ... Read More
Melphalan | 合法藥品大搜索
Melphalan is an Alkylating Drug. The mechanism of action of melphalan is as an Alkylating Activity. FDA Pharm Classes ... Read More
Alkeran | 合法藥品大搜索
Mechanism of Action. Mechorethamine derivative that inhibits DNA & RNA synthesis via formation of carbonium ions; cross links DNA strands (interstrand and ... Read More
Melphalan | 合法藥品大搜索
Usually, the drugs work by damaging the RNA or DNA that tells the cell how to copy itself in division. If the cells are unable to divide, they die. The faster the cells ... Read More
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