Pyrazinamide | 合法藥品大搜索

Pyrazinamideisamedicationusedtotreattuberculosis....Foractivetuberculosis,itisoftenusedwithrifampicin,isoniazid,andeitherstreptomycinorethambutol.

Medication

Pyrazinamide is a medication used to treat tuberculosis.[2] For active tuberculosis, it is often used with rifampicin, isoniazid, and either streptomycin or ethambutol.[3] It is not generally recommended for the treatment of latent tuberculosis.[2] It is taken by mouth.[1]

Common side effects include nausea, loss of appetite, muscle and joint pains, and rash.[2][4] More serious side effects include gout, liver toxicity, and sensitivity to sunlight.[2] It is not recommended in those with significant liver disease or porphyria.[3] It is unclear if use during pregnancy is safe but it is likely okay during breastfeeding.[3] Pyrazinamide is in the antimycobacterial class of medications.[2] How it works is not entirely clear.[2]

Pyrazinamide was first made in 1936, but did not come into wide use until 1972.[5] It is on the World Health Organizations List of Essential Medicines.[6] Pyrazinamide is available as a generic medication.[2]

Pyrazinamide is ...