Chloroquine and hydroxychloroquine in coronavirus disease ... | 合法藥品大搜索

The use of CQ and HCQ in COVID-19 has been a focus of tremendous public attention. To scrutinize this, a systematic review was performed to identify studies where CQ and HCQ had been used to treat COVID-19. A PRISMA checklist was used to conduct a systematic review [56]. MEDLINE (National Library of Medicine, Bethesda, MD, USA) and EMBASE (Elsevier, New York, NY, USA) were searched from inception to 18 April 2020, using keywords chloroquine AND COVID-19, and hydroxychloroquine AND COVID-19, to find articles providing information on the efficacy and safety of these formulations in patients with SARS-CoV-2 infection. The search also included articles related to in vitro studies. There was no language barrier employed and searches were expanded using a snowballing method to retrieve relevant papers. Several clinical trial registries were also searched to identi...