Epothilone | 合法藥品大搜索
Epothilonesarenaturallyoccurringcytotoxicmacrolides,whichwereinitiallyisolatedfromamycobacterium.Theiranti‐tumouractivityissimilartothatofthe ...,Theepothilonesareaclassofpotentialcancerdrugs.Liketaxanes,theypreventcancercellsfromdividingbyinterferingwithtubulin,butinearlytrials ...,EpothiloneAisanepithilonethatisepothiloneCinwhichthedoublebondinthemacrocycliclactoneringhasbeenoxidisedtothecorrespondingepoxide(the ...,EpothiloneBisanepithilonethatisepithiloneDinwhichthedoublebondinthemacrocy...
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Epothilone | 合法藥品大搜索
Epothilones are naturally occurring cytotoxic macrolides, which were initially isolated from a mycobacterium. Their anti‐tumour activity is similar to that of the ... Read More
Epothilone | 合法藥品大搜索
The epothilones are a class of potential cancer drugs. Like taxanes, they prevent cancer cells from dividing by interfering with tubulin, but in early trials ... Read More
Epothilone A | 合法藥品大搜索
Epothilone A is an epithilone that is epothilone C in which the double bond in the macrocyclic lactone ring has been oxidised to the corresponding epoxide (the ... Read More
Epothilone B | 合法藥品大搜索
Epothilone B is an epithilone that is epithilone D in which the double bond in the macrocyclic ring has been oxidised to the corresponding epoxide (the S,S ... Read More
Epothilone D | 合法藥品大搜索
However, a synthetic epothilone derivative, TPI 287, readily crosses the blood–brain barrier and has been reported to accumulate in the brain over plasma ( ... Read More
Epothilone D | 合法藥品大搜索
Epothilone D | C27H41NO5S | CID 447865 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, ... Read More
Epothilone在轉移性乳癌治療的角色 | 合法藥品大搜索
因此為Anthracycline 及紫杉醇使用後再復發之病人找到一個新治療藥物是必要的,而Epothilone便是其選擇之一。 要探討此一問題,需先了解造成抗癌藥物抗藥性的 ... Read More
抗癌新藥Epothilone | 合法藥品大搜索
Ixabepilone(BMS-247550; epothilone)是新一代抗有絲分裂藥物,它雖然不屬於紫杉醇,但其作用機轉與紫杉醇類藥物(taxanes)類似。它最早係由一種具有細胞 ... Read More
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