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The therapeutic role of ivabradine in heart failure | 合法藥品大搜索

The therapeutic role of ivabradine in heart failure

由CBadu-Boateng著作·2018·被引用13次—Inthisreviewarticle,weexaminethemechanismofactionofivabradine,evaluatetheclinicaltrialsunderpinningitsapplicationinheartfailure ...

 The therapeutic role of ivabradine in heart failure

Ther Adv Chronic Dis. 2018 Nov; 9(11): 199–207.

Charles Badu-Boateng

Department of Medicine, Frimley Park Hospital, Frimley, Camberley, UK

Robert Jennings

Department of Medicine, Frimley Park Hospital, Frimley, Camberley, UK

Daniel Hammersley

Department of Cardiology, Kings College Hospital NHS Foundation Trust, Denmark Hill, London SE5 9RS, UK

Charles Badu-Boateng, Department of Medicine, Frimley Park Hospital, Frimley, Camberley, UK;

Received 2018 Feb 3; Accepted 2018 May 30.

This article has been cited by[1] other articles in PMC.Abstract

Heart failure represents a major global cause of morbidity and mortality. Ivabradine is a selective funny current (If) inhibitor, which acts on the sinoatrial node, resulting in a reduction in heart rate. Ivabradine is currently licensed for use in patients with symptomatic heart failure with reduced ejection fraction and a heart rate persistently at least 70 beats per minute in ...

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Ivabradine (Corlanor) for Heart Failure | 合法藥品大搜索
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Ivabradine | 合法藥品大搜索
由 M Reed 著作 · 2020 · 被引用 1 次 — Ivabradine blocks the channel responsible for the cardiac pacemaker current, I(f), which regulates heart rate. This results in ... Read More
The therapeutic role of ivabradine in heart failure | 合法藥品大搜索
由 C Badu-Boateng 著作 · 2018 · 被引用 13 次 — In this review article, we examine the mechanism of action of ivabradine, evaluate the clinical trials underpinning its application in heart failure ... Read More
Ivabradine: Uses | 合法藥品大搜索
Ivabradine acts by selectively inhibiting the "funny" channel pacemaker current (If) in the sinoatrial node in a dose-dependent fashion, resulting in a lower heart ... Read More
Ivabradine | 合法藥品大搜索
Mechanism of action — Ivabradine acts by allowing negative chronotropy in the sinoatrial structure thus reducing the heart rate via specific inhibition of ... Read More
Mechanism of Action | 合法藥品大搜索
Watch the Corlanor® mechanism of action video to learn about how the therapy works. See if Corlanor® may be right for your chronic heart failure patients. Read More
Corlanor (ivabradine) dosing | 合法藥品大搜索
Medscape - Heart failure dosing for Corlanor (ivabradine), frequency-based adverse effects, comprehensive ... ivabradine (Rx) ... Mechanism of Action. Read More
The Clinical Use of Ivabradine | 合法藥品大搜索
2017年9月25日 — The clinical use of ivabradine is predicated on its mechanism of action on sinoatrial nodal tissue where it selectively inhibits the funny current ... Read More
The Clinical Use of Ivabradine | 合法藥品大搜索
由 JS Koruth 著作 · 2017 · 被引用 72 次 — (A) Ivabradine's primary mechanism of action on cardiac tissue is on the sinoatrial (SA) node, which occupies a predominantly subepicardial ... Read More
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