Intravenous lacosamide in refractory seizure clusters and ... | 合法藥品大搜索

$Intravenous lacosamide in refractory seizure clusters and ...$

由BLegros著作·2014·被引用40次—Aftertheinitialpartofthestudy,andduetopoorresultswiththisdosage,asecondgroupreceivedaloadingdoseof400mg.Outcomemeasuresincluded ...

$Intravenous lacosamide in refractory seizure clusters and ...$

Background: The treatment of refractory status epilepticus (RSE) remains largely empirical. Lacosamide (LCM) is a new anticonvulsant available in intravenous (IV) form, but its optimal dosing regimen for the treatment of RSE is unknown. We compared safety and efficacy of two loading doses: 200 and 400 mg.

Methods: Prospective observational study of all patients who received IV LCM for RSE or seizure clusters between October 2010 and December 2012. A first group received an IV load of 200 mg of LCM. After the initial part of the study, and due to poor results with this dosage, a second group received a loading dose of 400 mg. Outcome measures included response rate, time to response, and adverse events.

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Vimpat (lacosamide) dosing, indications | 合法藥品大搜索

Medscape - Seizure dosing for Vimpat (lacosamide), frequency-based ... initial loading dose schedule: 200 mg PO/IV as a single loading dose, followed 12 hr ... Read More

Safety and tolerability of adjunctive lacosamide ... | 合法藥品大搜索

由 NB Fountain 著作 · 2013 · 被引用 42 次 — An intravenous lacosamide loading dose (200, 300, or 400 mg) was administered over 15 min followed 12 h later by initiation of oral dosing ... Read More

Safety & pK of IV loading dose of lacosamide in the ICU | 合法藥品大搜索

由 RE Ramsay 著作 · 2015 · 被引用 16 次 — A restrospective review of patients treated in the ICU for refractory status epilepticus who had received an initial IV loading dose of lacosamide ... Read More

Intravenous lacosamide in refractory seizure clusters and ... | 合法藥品大搜索

由 B Legros 著作 · 2014 · 被引用 40 次 — After the initial part of the study, and due to poor results with this dosage, a second group received a loading dose of 400 mg. Outcome measures included ... Read More

Intravenous Lacosamide in Pediatric Status Epilepticus | 合法藥品大搜索

由 K Poddar 著作 · 2016 · 被引用 27 次 — Results: Nine children with a mean age of 5.7 years (range: three months to 16 years) were included. The mean initial or loading dose was 8.7 mg/kg, with seven ... Read More

Loading Dose Administration | 合法藥品大搜索

MONOTHERAPY DOSING FOR ADULT PATIENTS | ... (Tablets not shown at actual size.) ... 300 mg/day to 400 mg/day (150 mg-200 mg twice-daily). Titrate based on ... Read More

Loading Dose Trial Data | 合法藥品大搜索

200 mg Loading Dose in Adult Patients · USE THE VIMPAT LOADING DOSE WHEN YOUR ADULT PATIENTS NEED TO GET TO A THERAPEUTIC DOSE MORE ... Read More

Lacosamide Dosage Guide + Max Dose | 合法藥品大搜索

2020年12月29日 — Detailed Lacosamide dosage information for adults and children. ... LOADING DOSE: 200 mg oral/IV once, followed in 12 hours with 100 mg ... Read More