Intravenous Lacosamide in Pediatric Status Epilepticus | 合法藥品大搜索

由KPoddar著作·2016·被引用27次—Results:Ninechildrenwithameanageof5.7years(range:threemonthsto16years)wereincluded.Themeaninitialorloadingdosewas8.7mg/kg,withseven ...

Introduction: Lacosamide is an antiepilepsy drug approved by the Food and Drug Administration for patients aged 17 years and older for partial-onset seizures as monotherapy or adjunctive therapy. We reviewed the use of intravenous lacosamide in children aged less than 17 years with status epilepticus.

Methods: Children who received at least one dose of intravenous lacosamide for status epilepticus at our tertiary care childrens hospital from December 2011 to March 2014 were studied. Status epilepticus was defined as continuous seizure activity for longer than 20 minutes or two or more recurrent seizures without regaining baseline level of awareness. Efficacy was defined as seizure freedom or more than 50% reduction of seizures within 24 hours of administering lacosamide.

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Vimpat (lacosamide) dosing, indications | 合法藥品大搜索

Medscape - Seizure dosing for Vimpat (lacosamide), frequency-based ... initial loading dose schedule: 200 mg PO/IV as a single loading dose, followed 12 hr ... Read More

Safety and tolerability of adjunctive lacosamide ... | 合法藥品大搜索

由 NB Fountain 著作 · 2013 · 被引用 42 次 — An intravenous lacosamide loading dose (200, 300, or 400 mg) was administered over 15 min followed 12 h later by initiation of oral dosing ... Read More

Safety & pK of IV loading dose of lacosamide in the ICU | 合法藥品大搜索

由 RE Ramsay 著作 · 2015 · 被引用 16 次 — A restrospective review of patients treated in the ICU for refractory status epilepticus who had received an initial IV loading dose of lacosamide ... Read More

Intravenous lacosamide in refractory seizure clusters and ... | 合法藥品大搜索

由 B Legros 著作 · 2014 · 被引用 40 次 — After the initial part of the study, and due to poor results with this dosage, a second group received a loading dose of 400 mg. Outcome measures included ... Read More

Intravenous Lacosamide in Pediatric Status Epilepticus | 合法藥品大搜索

由 K Poddar 著作 · 2016 · 被引用 27 次 — Results: Nine children with a mean age of 5.7 years (range: three months to 16 years) were included. The mean initial or loading dose was 8.7 mg/kg, with seven ... Read More

Loading Dose Administration | 合法藥品大搜索

MONOTHERAPY DOSING FOR ADULT PATIENTS | ... (Tablets not shown at actual size.) ... 300 mg/day to 400 mg/day (150 mg-200 mg twice-daily). Titrate based on ... Read More

Loading Dose Trial Data | 合法藥品大搜索

200 mg Loading Dose in Adult Patients · USE THE VIMPAT LOADING DOSE WHEN YOUR ADULT PATIENTS NEED TO GET TO A THERAPEUTIC DOSE MORE ... Read More

Lacosamide Dosage Guide + Max Dose | 合法藥品大搜索

2020年12月29日 — Detailed Lacosamide dosage information for adults and children. ... LOADING DOSE: 200 mg oral/IV once, followed in 12 hours with 100 mg ... Read More