Quinolone antibiotic | 合法藥品大搜索

Mechanismofaction—Themechanismsofthetoxicityoffluoroquinoloneshavebeenattributedtotheirinteractionswithdifferentreceptorcomplexes, ...

Class of antibacterial drugs, subgroup of quinolones

Quinolone antibiotics constitute a large group of broad-spectrum bacteriocidals that share a bicyclic core structure related to the substance 4-quinolone.[1] They are used in human and veterinary medicine to treat bacterial infections, as well as in animal husbandry, specifically poultry production.[2]

Nearly all quinolone antibiotics in use are fluoroquinolones, which contain a fluorine atom in their chemical structure and are effective against both Gram-negative and Gram-positive bacteria. One example is ciprofloxacin, one of the most widely used antibiotics worldwide.[3][4]

Fluoroquinolones are often used for genitourinary infections and are widely used in the treatment of hospital-acquired infections associated wit...