Reye's syndrome | 合法藥品大搜索

由JFTGlasgow著作·2006·被引用67次—Reye'ssyndromeisaserious,acuteencephalopathythathasbeenlinkedwithaspirin(acetylsalicylicacid)useinchildrenandteenagers<18yearsofage.

Reyes syndrome is a serious, acute encephalopathy that has been linked with aspirin (acetylsalicylic acid) use in children and teenagers <18 years of age. Although others may disagree, it is my belief that any objective analysis of published material in the last 20 years must conclude that there is a close link between the devastating encephalopathy Reyes syndrome and ingestion of aspirin during the febrile prodrome. The drug appears to act as a co-factor in susceptible individuals. Although some of the epidemiological data indicate an association between the two, the burden of evidence suggests actual causality and is both consistent and specific as well as strong and time related. Some of the evidence points to illness severity being dose related although it seems that in the presence of a viral infection, no dose of aspirin can be considered safe. No published work, using methodology that can be critically evaluated, has ...