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Dolutegravir | 合法藥品大搜索

Dolutegravir

Dolutegravir(DTG),soldunderthebrandnameTivicay,isanantiretroviralmedicationused,...Jumpupto:Tivicay-dolutegravirsodiumtablet,filmcoated.

 Dolutegravir

Chemical compound

DolutegravirTrade namesTivicay, Tivicay PDOther namesGSK572, S-349572AHFS/Drugs.comMonographMedlinePlusa613043License data PregnancycategoryRoutes ofadministrationBy mouthATC codeLegal status Bioavailabilityn/a[4]Protein binding≥98.9%MetabolismUGT1A1 and CYP3AElimination half-life~14 hoursExcretionFeces (53%) and urine (18.9%)

(4R,12aS)-N-(2,4-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1,2:4,5]pyrazino[2,1-b] [1,3]oxazine-9-carboxamide

CAS NumberPubChem CIDIUPHAR/BPSDrugBankChemSpiderUNIIKEGGChEBIChEMBLPDB ligandCompTox Dashboard (EPA)ECHA InfoCard100.237.735 FormulaC20H19F2N3O5Molar mass419.385 g·mol−13D model (JSmol)

C[C@@H]1CCO[C@@H]2N1C(=O)c3c(c(=O)c(cn3C2)C(=O)NCc4ccc(cc4F)F)O

InChI=1S/C20H19F2N3O5/c1-10-4-5-30-15-9-24-8-13(17(26)18(27)16(24)20(29)25(10)15)19(28)23-7-11-2-3-12(21)6-14(11)22/h2-3,6,8,10,15,27H,4-5,7,9H2,1H3,(H,23,28)/t10-,15+/m1/s1 YKey:RHWKPHLQXYSBKR-BMIGLBTASA-N Y NY (what is this?)  (...

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Dolutegravir sodium | 合法藥品大搜索
Dolutegravir Sodium is the sodium salt form of dolutegravir, an orally bioavailable integrase strand-transfer inhibitor (INSTI), with activity against human ... Read More
Dolutegravir sodium | 合法藥品大搜索
Dolutegravir sodiumProduct ingredient for Dolutegravir ... Dolutegravir is a HIV-1 intergrase inhibitor that blocks the strand transfer step of the integration of the viral ... Read More
TIVICAY(dolutegravir) | 合法藥品大搜索
Each tablet contains 50 mg of dolutegravir (as. 31 dolutegravir sodium) [see Description (11)]. 32. 4. CONTRAINDICATIONS. 33. Coadministration of TIVICAY​ ... Read More
Dolutegravir | 合法藥品大搜索
Dolutegravir (DTG), sold under the brand name Tivicay, is an antiretroviral medication used, ... Jump up to: Tivicay- dolutegravir sodium tablet, film coated. Read More
Dolutegravir | 合法藥品大搜索
2020年8月15日 — Why is this medication prescribed? ... Dolutegravir is used with other medications to treat human immunodeficiency virus (HIV) infection in adults ... Read More
KEGG DRUG | 合法藥品大搜索
J05AJ03 Dolutegravir D10113 Dolutegravir sodium (JAN/USAN) <JP/US> USP drug classification [BR:br08302] Antivirals Anti-HIV Agents, Integrase Inhibitors ... Read More
Tivicay 10 mg Film | 合法藥品大搜索
Each film-coated tablet contains dolutegravir sodium equivalent to 50 mg dolutegravir. For the full list of excipients, see section 6.1. 3. Pharmaceutical form. Film- ... Read More
Tivicay 25 mg Film | 合法藥品大搜索
Each film-coated tablet contains dolutegravir sodium equivalent to 50 mg dolutegravir. For the full list of excipients, see section 6.1. 3. Pharmaceutical form. Film- ... Read More
Dolutegravir Sodium | ≥99%(HPLC) | 合法藥品大搜索
Dolutegravir Sodium (GSK-1349572A) is a HIV integrase inhibitor with IC50 of 2.7 nM. Size, Price, Stock, Quantity. 5mg, EUR 144, In stock. Read More
Dolutegravir - Tablet (film coated) | 合法藥品大搜索
TIVICAY PD Tablets for Oral Suspension: Each tablet contains 5 mg of dolutegravir (as dolutegravir sodium). Tablets are white, round, strawberry cream flavored, ... Read More
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