Late Sodium Current Blocker (Ranolazine) | 合法藥品大搜索

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由 BM Reddy 著作 · 2010 · 被引用 41 次 — Ranolazine's initial mechanism of action was thought to be the inhibition of cardiac metabolism of fatty acids. However, the concentration of the drug that ... Read More

由 C Marx 著作 · 2006 · 被引用 8 次 — The proposed ranolazine mechanism of action is the inhibition of pathologic increases in late Na+ current induced during myocardial ischemia. Read More

The mechanism of action for ranolazine is not fully understood. At therapeutic concentrations, it can inhibit the cardiac late sodium 205 current (INa), which ... Read More

Mechanism of Action. Ranolazine represents a new class of antianginal drugs. It blocks late inward sodium currents in cardiomyocytes. Read More

Mechanism of action — Mechanism of action[edit]. Ranolazine inhibits persistent or late inward sodium current (INa) in heart muscle in a variety of ... Read More

由 L Belardinelli 著作 · 2006 · 被引用 96 次 — Sodium channels and the action of ranolazine ... Electrical excitation causes sodium ions to enter cardiac cells through membrane sodium channels. Read More

2021年6月29日 — Mechanism of Action ... The mechanism of ranolazine's anti-anginal and anti-ischemic effects is not well understood. It inhibits late sodium ... Read More

2016年3月15日 — New‐Onset and Paroxysmal Atrial Fibrillation. The mechanism of action of ranolazine has been proposed to reduce atrial excitability and prolong ... Read More

由 JR Anderson 著作 · 2005 · 被引用 30 次 — While the mechanism of action of ranolazine is not completely understood, it is believed to involve a reduction in fatty acid oxidation, ultimately leading ... Read More