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Enzymatic hydrolysis of the β-lactam ring — β-lactam antibiotics (beta-lactam antibiotics) are antibiotics that contain a beta-lactam ring in their ... Read More

A traditional template for antibiotics is the β-lactam ring and many novel entities have been produced by varying the attached appendages. Thiadiazole (43), a β ... Read More

β-Lactams remain one of the most commonly involved medications in allergic drug reactions. The four main groups share in common a four-member β-lactam ring; and ... Read More

由 K Tahlan 著作 · 2013 · 被引用 48 次 — Biosynthetic studies have shown that the β-lactam class of natural products can be divided into at least four different subgroups based on the ... Read More

由 N Pandey 著作 · 2020 · 被引用 29 次 — Beta-lactam antibiotics are used in the management and treatment of bacterial infections. This activity will highlight the mechanism of ... Read More

β-Lactam Antibiotics Bearing More Than One β-Lactam Ring · 由 M De Rosa 著作 · 2021 — In penicillins, cephalosporins, and carbapenems, this ring is fused to ... Read More

由 MI Konaklieva 著作 · 2014 · 被引用 60 次 — The electrophilic β-lactam ring is amenable for the inhibition of different enzyme classes by a suitable decoration of the core scaffold. Read More

由 K Tahlan 著作 · 2013 · 被引用 48 次 — Isopenicillin N synthase is responsible for formation of the β-lactam ring in all penicillin/cephalosporin compounds, and the reaction catalyzed is completely ... Read More